Very recently, Zika virus (ZIKV) has gained a medical importance following the large-scale epidemics in South Pacific and Latin America. This paper reviews information on the epidemiology and clinical features of Zika disease with a particular emphasis on the host-virus interactions that contribute to the pathogenicity of ZIKV in humans.
Keywords: Arbovirus; Epidemiology; Host-pathogen interactions; Innate immunity; Vector; ZIKA.
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