Role of Endoscopic Ultrasonography and Endoscopic Retrograde Cholangiopancreatography in the Clinical Assessment of Pancreatic Neoplasms

Surg Oncol Clin N Am. 2016 Apr;25(2):255-72. doi: 10.1016/j.soc.2015.11.004.

Abstract

Accurate diagnosis and staging of pancreatic neoplasms is essential for surgical planning and identification of locally advanced and metastatic disease that is incurable by surgery. The ability to position the endoscopic ultrasonography (EUS) transducer close to the pancreas combined with the use of fine-needle aspiration enables the accurate diagnosis of pancreatic cysts and solid masses. EUS is also increasingly being used to procure core tissue for molecular analysis that facilitates personalized treatment of pancreatic cancer. Various therapeutic interventions can be undertaken under EUS guidance. This article focuses on the applications of EUS and endoscopic retrograde cholangiopancreatography in pancreatic neoplasms.

Keywords: Biliary decompression; Endoscopic retrograde cholangiopancreatography; Endoscopic ultrasonography; Fine-needle aspiration; Pancreatic cancer; Pancreatic cyst neoplasm.

Publication types

  • Review

MeSH terms

  • Biomarkers
  • Biopsy, Needle
  • Cholangiopancreatography, Endoscopic Retrograde*
  • Drainage
  • Endosonography*
  • Humans
  • Jaundice, Obstructive / etiology
  • Jaundice, Obstructive / therapy*
  • Pancreas / diagnostic imaging*
  • Pancreatic Neoplasms / diagnosis*
  • Pancreatic Neoplasms / diagnostic imaging
  • Pancreatic Neoplasms / pathology
  • Prognosis
  • Prosthesis Implantation
  • Stents
  • Ultrasonography, Interventional

Substances

  • Biomarkers