Rice bran nutraceutics: A comprehensive review

Crit Rev Food Sci Nutr. 2017 Nov 22;57(17):3771-3780. doi: 10.1080/10408398.2016.1164120.


Agro-industry yields ample quantity of several byproducts with considerable importance. These byproducts are mostly under-utilized, often used as animal feed or rejected as waste; hence their true potential is not harnessed. The use of such superfluous resources is of not only economic significance but also a form of commercial recycling. Rice bran is an important byproduct of rice milling industry with a global potential of 29.3 million tons annually. It is gaining great attention of the researchers due to its nutrient-rich composition, easy availability, low cost, high antioxidant potential, and promising effects against several metabolic ailments. Bioactive components of rice bran, mainly γ-oryzanol, have been reported to possess antioxidant, anti-inflammatory, hypocholesterolemic, anti-diabetic, and anti-cancer activities. Rice bran oil contains appreciable quantities of bioactive components and has attained the status of "Heart oil" due to its cardiac-friendly chemical profile. Nutraceutics have successfully been extracted from rice bran using several extraction techniques such as solvent extraction, supercritical fluid extraction, microwave-, and ultrasonic-assisted extraction. Current paper is an attempt to highlight bioactive moieties of rice bran along with their extraction technologies and health benefits.

Keywords: Rice bran; bioactive components; diabetes; hypercholesterolemia; γ-oryzanol.

Publication types

  • Review

MeSH terms

  • Animal Feed
  • Animals
  • Antioxidants
  • Humans
  • Nutritive Value
  • Oryza / chemistry*
  • Phenylpropionates / analysis*
  • Rice Bran Oil / analysis*


  • Antioxidants
  • Phenylpropionates
  • Rice Bran Oil
  • gamma-oryzanol