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Review
, 6 (1), 101-4

Study Design in Evidence-Based Surgery: What Is the Role of Case-Control Studies?

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Review

Study Design in Evidence-Based Surgery: What Is the Role of Case-Control Studies?

Amy M Cao et al. World J Methodol.

Abstract

Randomized controlled trials (RCTs) are the gold standard in terms of study design, however, in the surgical setting conducting RCTs can often be unethical or logistically impossible. Case-control studies should become the major study design used in surgical research when RCTs are unable to be conducted and definitely replacing case series which offer little insight into surgical outcomes and disease processes.

Keywords: Bias; Case-control studies; Randomized clinical trials; Research studies; Sample size.

Figures

Figure 1
Figure 1
Hierarchy of study design.

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