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Review
. 2016 Jan;43(1):13-8.
doi: 10.1159/000441612. Epub 2015 Oct 29.

Transfusion Support for ABO-Incompatible Progenitor Cell Transplantation

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Free PMC article
Review

Transfusion Support for ABO-Incompatible Progenitor Cell Transplantation

Patricia M Kopko. Transfus Med Hemother. .
Free PMC article

Abstract

ABO-incompatible transplants comprise up to 50% of allogeneic progenitor cell transplants. Major, minor and bidirectional ABO-incompatible transplants each have unique complications that can occur, including hemolysis at the time of progenitor cell infusion, hemolysis during donor engraftment, passenger lymphocyte syndrome, delayed red blood cell engraftment, and pure red cell aplasia. Appropriate transfusion support during the different phases of the allogeneic progenitor cell transplant process is an important part of ABO-incompatible transplantation.

Keywords: ABO-incompatible transplant; Platelet transfusion; Transfusion.

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