Proteinuria--what value is the dipstick?

Br J Urol. 1989 Feb;63(2):202-8. doi: 10.1111/j.1464-410x.1989.tb05166.x.

Abstract

The value of the urinary dipstick in the assessment of proteinuria was investigated in a study correlating laboratory measurements of protein and albumin against the dipstick protein in the same samples of urine; 94 patients (100 admissions) were studied at the Royal Air Force Renal Unit, each patient collecting two 24-h urine samples. Along with each 24-h sample, 10-ml aliquots of urine were obtained at 3 designated times during the day for both ward dipstick testing and laboratory assay; + or more on the dipstick correlated with abnormal proteinuria (greater than or equal to 150 mg/24 h) in 88% of cases, whilst trace values straddled the level of significant proteinuria. Further differentiation of trace was possible by repeat testing during the day. The subsequent presence of a dipstick negative during that day correlated with normality in all but 5% of cases. In order to ensure detection of renal disease presenting as isolated orthostatic proteinuria, assay of the mid-morning sample is recommended.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Albuminuria / urine
  • Child
  • Creatinine / urine
  • Female
  • Humans
  • Male
  • Middle Aged
  • Posture
  • Predictive Value of Tests
  • Proteinuria / urine*
  • Reagent Kits, Diagnostic*
  • Time Factors

Substances

  • Reagent Kits, Diagnostic
  • Creatinine