Biomechanical, micro-computed tomographic and immunohistochemical analysis of early osseous integration at titanium implants placed following lateral ridge augmentation using extracted tooth roots

Clin Oral Implants Res. 2017 Mar;28(3):334-340. doi: 10.1111/clr.12803. Epub 2016 Mar 29.

Abstract

Objectives: To assess biomechanical, micro-computed tomographic (micro CT) and immunohistochemical characteristics of early osseous integration at titanium implants placed following lateral ridge augmentation using autogenous extracted tooth roots.

Material & methods: The roots of healthy maxillary premolars (PM) and retromolar cortical autogenous bone (AB) blocks were used for lateral ridge augmentation at chronic-type defects in the lower quadrants of n = 16 foxhounds. At 12 weeks, titanium implants were inserted and left to heal for another 3 weeks. Osteocalcin (OC) antigen reactivity, removal torque values (RT) and the bone volume per tissue volume (micro CT- BV/TV) along the implants were assessed.

Results: Median OC (PM: 6.71 vs. AB: 2.73%), RT (PM: 61.97 vs. AB: 44.8 Ncm) and BV/TV (PM: 0.34 vs. AB: 0.21) values were comparable in both PM and AB groups.

Conclusions: PM and AB grafted sites equally supported the early stages of osseointegration.

Keywords: alveolar ridge augmentation; animal experiment; histological technique; tooth transplantation.

MeSH terms

  • Alveolar Ridge Augmentation*
  • Animals
  • Biomechanical Phenomena
  • Dental Implantation, Endosseous
  • Dental Implants*
  • Dental Prosthesis Design
  • Dogs
  • Immunohistochemistry
  • Mandible / anatomy & histology
  • Mandible / diagnostic imaging
  • Mandible / physiology*
  • Mandible / surgery
  • Osseointegration*
  • Titanium*
  • Tomography, X-Ray Computed / methods
  • Tooth Extraction
  • Tooth Root

Substances

  • Dental Implants
  • Titanium