There was performed a comparative analysis of the actual nutrition of inhabitants of the city of Omsk with mixed feeding (n = 50), and representatives of different types of vegetarians: raw food diet (n = 12), veganism (n = 14), lacto-ovo vegetarians (n = 14). There were revealed differences in consumption of food and food substances in persons with different types of food. There was established insufficient energy value, reduced intake of protein, fats, carbohydrates, vitamin B12 in the diet of vegans and raw foodists. There was determined the availability of vitamin B12 by the analysis of this substance in the blood serum by mean of standard chemiluminescent immunoassay. Vitamin B12 deficiency was revealed in vegans and raw foodists. There were substantiated such basic directions ofelimination of the deficit of nutrients and calories in the diet of vegetarians as the careful planning and assortment of products, as well as the use of vitamin-mineral complexes.