Pragmatic Randomized Clinical Trials: A Proposal to Enhance Evaluation of New Cancer Therapies With Early Signs of Exceptional Activity

Ann Oncol. 2016 Jul;27(7):1342-8. doi: 10.1093/annonc/mdw143. Epub 2016 Mar 30.

Publication types

  • Editorial

MeSH terms

  • Antineoplastic Agents / therapeutic use*
  • Drug Evaluation / methods
  • Drug Evaluation / trends
  • Humans
  • Neoplasms / diagnosis
  • Neoplasms / drug therapy*
  • Patient Selection
  • Piperazines / therapeutic use
  • Pragmatic Clinical Trials as Topic / methods*
  • Pyrazoles / therapeutic use
  • Pyridines / therapeutic use
  • Pyrimidines / therapeutic use
  • Randomized Controlled Trials as Topic / methods*
  • Research Design / trends

Substances

  • Antineoplastic Agents
  • PCI 32765
  • Piperazines
  • Pyrazoles
  • Pyridines
  • Pyrimidines
  • palbociclib