Effects of Millimetric Shifts in Breast Cancer Radiotherapy on the Radiation Dose Distribution

Asian Pac J Cancer Prev. 2016;17(3):1197-9. doi: 10.7314/apjcp.2016.17.3.1197.

Abstract

Background: This study aimed to facilitate decision-making in cases of breast cancer radiotherapy shifts by simulating millimetric shifts and analyzing their effects on dose distribution.

Methods: The study included 30 patients with left side breast cancer who were treated with three dimensional conformal radiotherapy (3D-CRT) in the Radiation Oncology Department in Hatay Public Hospital, between January 2013 and April 2015. A treatment plan shifting at three axes with six different measures was simulated.

Results: The biggest difference in values was (+3mm shift) 476cGy, with a 7.7 % change for heart and 25.6% for spinal cord. The shifts in values respectively for CTV min, mean, max were -4.8%, 2.5%, 4%. The differences for lymphatic min, mean, max were 21.3%, 20.3%, -12.2%.

Conclusion: The most important thing is not the treatment plan quality, but its practicality. The treatment plan must be practical and its practice must be controlled rigidly.

MeSH terms

  • Adult
  • Aged
  • Breast Neoplasms / pathology
  • Breast Neoplasms / radiotherapy*
  • Computer Simulation
  • Female
  • Follow-Up Studies
  • Humans
  • Lymphatic Irradiation / methods*
  • Middle Aged
  • Neoplasm Staging
  • Organs at Risk / radiation effects*
  • Prognosis
  • Radiotherapy Dosage
  • Radiotherapy Planning, Computer-Assisted / methods*
  • Radiotherapy, Conformal / methods*