Diaper Dermatitis: A Review of 63 Children

Pediatr Dermatol. 2016 May;33(3):332-6. doi: 10.1111/pde.12860. Epub 2016 Apr 4.

Abstract

Background/objective: Diaper dermatitis (DD) is a common infantile dermatosis with a highly variable prevalence and incidence. This study aimed to present the demographic and clinical features of babies with DD.

Methods: Data, including demographic and clinical features, obtained from DD patient forms were retrospectively analyzed.

Results: The study included 63 babies with DD (female: n = 35 [55.6%]; male: n = 28 [44.4%]; mean age 11.6 mos). Most of the patients (43.5%) were 0 to 6 months of age. In all, 76.3% were breastfed, of whom 31.7% were exclusively breastfed. The number of previous episodes of DD was significantly lower in breastfed babies. The most common diaper area cleansing method was wet wipes (54.1%). Diaper creams were used in 86.2% of patients. DD was severe in 22.2% of patients, moderate in 57.4%, and mild in 20.4%. Candida infection was noted in 77.4% of patients. The median number of previous episodes of DD was significantly higher in patients with Candida infection than in those without (p = 0.02). Treatment yielded greater than 50% improvement (complete and moderate response) in 59.4% of patients at the first follow-up visit (3-5 days) and 82.6% at the second follow-up visit (10 days).

Conclusion: Most babies with DD were 0 to 6 months of age. Breastfed babies had fewer previous episodes of DD, so mothers should be encouraged to breastfeed their babies to reduce the incidence of DD. Candida infection was common; clinicians should be aware of its association with DD.

MeSH terms

  • Administration, Topical
  • Antifungal Agents / therapeutic use
  • Chi-Square Distribution
  • Databases, Factual
  • Dermatitis, Irritant / diagnosis
  • Dermatitis, Irritant / drug therapy
  • Dermatitis, Irritant / epidemiology
  • Dermatologic Agents / therapeutic use*
  • Diaper Rash / diagnosis*
  • Diaper Rash / drug therapy*
  • Diaper Rash / epidemiology
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Male
  • Prednisolone / therapeutic use
  • Retrospective Studies
  • Risk Assessment
  • Severity of Illness Index
  • Skin Care / methods*
  • Statistics, Nonparametric
  • Treatment Outcome

Substances

  • Antifungal Agents
  • Dermatologic Agents
  • Prednisolone