Medication Management of Jaw Lesions for Dental Patients

Dent Clin North Am. 2016 Apr;60(2):483-95. doi: 10.1016/j.cden.2015.11.004. Epub 2016 Jan 26.


Most pathologic lesions of the jaws or of oral mucosa are treated successfully by surgical interventions. For treatment of the central giant cell lesion, aneurysmal bone cysts, histiocytosis of the mandible, hemangioma, odontogenic keratocyst, Paget disease, oral submucous fibrosis, and oral lichen planus, medical management consisting of intralesional injections, sclerosing agents, and systemic bisphosphonates is as successful as surgical procedures with fewer complications. Pharmacology of agents used and protocols are presented.

Keywords: Giant cell lesion; Inralesional injections; Jaw lesions; Sclerosing agent.

Publication types

  • Review

MeSH terms

  • Diphosphonates
  • Humans
  • Jaw
  • Jaw Diseases / surgery
  • Jaw Diseases / therapy*
  • Mouth Mucosa
  • Odontogenic Cysts
  • Odontogenic Tumors


  • Diphosphonates