Lymphangioma Circumscriptum: Good Clinical Response to Isotretinoin Therapy

Pediatr Dermatol. 2016 May;33(3):e208-9. doi: 10.1111/pde.12839. Epub 2016 Apr 4.

Abstract

Lymphangioma circumscriptum (LC) is a superficial form of lymphatic malformation that can be difficult to treat. Therapeutic approaches to LC such as laser therapy, sclerotherapy, and surgical excision give varying results. This is the first description of a case of LC successfully treated with oral isotretinoin. Further studies are needed to confirm whether this is a reproducible treatment option.

Publication types

  • Case Reports

MeSH terms

  • Administration, Oral
  • Adolescent
  • Biopsy, Needle
  • Dose-Response Relationship, Drug
  • Drug Administration Schedule
  • Female
  • Follow-Up Studies
  • Humans
  • Immunohistochemistry
  • Isotretinoin / therapeutic use*
  • Keratolytic Agents / therapeutic use*
  • Lymphangioma / diagnosis*
  • Lymphangioma / drug therapy*
  • Skin Neoplasms / diagnosis
  • Skin Neoplasms / drug therapy*
  • Thigh
  • Treatment Outcome

Substances

  • Keratolytic Agents
  • Isotretinoin