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Randomized Controlled Trial
, 22 (1), 96-106

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial

Randomized Controlled Trial

Body Weight Management in Adults Under Chronic Stress Through Treatment With Ashwagandha Root Extract: A Double-Blind, Randomized, Placebo-Controlled Trial

Dnyanraj Choudhary et al. J Evid Based Complementary Altern Med.

Abstract

Chronic stress has been associated with a number of illnesses, including obesity. Ashwagandha is a well-known adaptogen and known for reducing stress and anxiety in humans. The objective of this study was to evaluate the safety and efficacy of a standardized root extract of Ashwagandha through a double-blind, randomized, placebo-controlled trial. A total of 52 subjects under chronic stress received either Ashwagandha (300 mg) or placebo twice daily. Primary efficacy measures were Perceived Stress Scale and Food Cravings Questionnaire. Secondary efficacy measures were Oxford Happiness Questionnaire, Three-Factor Eating Questionnaire, serum cortisol, body weight, and body mass index. Each subject was assessed at the start and at 4 and 8 weeks. The treatment with Ashwagandha resulted in significant improvements in primary and secondary measures. Also, the extract was found to be safe and tolerable. The outcome of this study suggests that Ashwagandha root extract can be used for body weight management in adults under chronic stress.

Keywords: Withania somnifera; food craving; serum cortisol; stress; weight gain.

Conflict of interest statement

Declaration of Conflicting Interests: The authors declared no potential conflicts of interest with respect to the research, authorship, and/or publication of this article.

Figures

Figure 1.
Figure 1.
CONSORT (Consolidated Standards of Reporting Trials) flow diagram. Patient distribution and study design.

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References

    1. Chandrasekhar K, Kapoor J, Anishetty S. A prospective, randomized double-blind, placebo-controlled study of safety and efficacy of a high-concentration full-spectrum extract of ashwagandha root in reducing stress and anxiety in adults. Indian J Psychol Med. 2012;34:255–262. doi:10.4103/0253-7176.106022. - PMC - PubMed
    1. Nevanperä NJ, Hopsu L, Kuosma E, Ukkola O, Uitti J, Laitinen JH. Occupational burnout, eating behavior, and weight among working women. Am J Clin Nutr. 2012;95:934–943. doi:10.3945/ajcn.111.014191. - PubMed
    1. Cooley K, Szczurko O, Perri D, et al. Naturopathic care for anxiety: A randomized controlled trial ISRCTN78958974. PLoS One. 2009;4(8):e6628 doi:10.1371/journal.pone.0006628. - PMC - PubMed
    1. Kyrou I, Tsigos C. Chronic stress, visceral obesity and gonadal dysfunction. Hormones. 2008;7:287–293. - PubMed
    1. Tsutsumi A, Kayaba K, Yoshimura M, et al. ; Jichi Medical School Cohort Study Group. Association between job characteristics and health behaviors in Japanese rural workers. Int J Behav Med. 2003;10:125–142. doi:10.1207/S15327558IJBM1002_03. - PubMed

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