Australasian Society of Infectious Diseases updated guidelines for the management of Clostridium difficile infection in adults and children in Australia and New Zealand

Intern Med J. 2016 Apr;46(4):479-93. doi: 10.1111/imj.13027.


The incidence of Clostridium difficile infection (CDI) continues to rise, whilst treatment remains problematic due to recurrent, refractory and potentially severe nature of disease. The treatment of C. difficile is a challenge for community and hospital-based clinicians. With the advent of an expanding therapeutic arsenal against C. difficile since the last published Australasian guidelines, an update on CDI treatment recommendations for Australasian clinicians was required. On behalf of the Australasian Society of Infectious Diseases, we present the updated guidelines for the management of CDI in adults and children.

Keywords: Clostridium difficile; faecal microbiota transplant (FMT); fidaxomicin; metronidazole; treatment; vancomycin.

MeSH terms

  • Adult
  • Australasia / epidemiology
  • Australia / epidemiology
  • Clostridioides difficile* / isolation & purification
  • Clostridium Infections / diagnosis
  • Clostridium Infections / epidemiology*
  • Clostridium Infections / therapy*
  • Communicable Diseases / diagnosis
  • Communicable Diseases / epidemiology
  • Communicable Diseases / therapy
  • Disease Management*
  • Humans
  • New Zealand / epidemiology
  • Practice Guidelines as Topic / standards*
  • Societies, Medical / standards*
  • Societies, Medical / trends