Microfluidic Synthesis of Nanoparticles and their Biosensing Applications

Crit Rev Anal Chem. 2016 Nov;46(6):538-61. doi: 10.1080/10408347.2016.1169912. Epub 2016 Apr 12.

Abstract

We present an extensive overview of the evolution and progress made in the field of microstructures and nanostructures preparation using microfluidic techniques in recent times. A microfluidic system creates particles that are within a narrow range of shape and size distribution. It enables controlling the shape, size and composition of nanomaterials (NMs) for various applications. A brief evaluation of the advantages of both droplet-based and continuous flow synthesis of nanoparticles (NPs) is discussed in detail and compared with the traditional wet chemical batch synthesis approach. Due to increasing applications of biosensing, nanobiotechnology, nanomedicine and diagnostics devices, special attention should be paid to metal NPs developed through microfluidic routes.

Keywords: Biosensing; microfluidic; nano-diagnostics; noble metal nanoparticles; sensing.

Publication types

  • Review

MeSH terms

  • Biosensing Techniques / methods*
  • Microfluidic Analytical Techniques*
  • Nanoparticles / chemistry*