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. 2016 Apr 13;11(4):e0152367.
doi: 10.1371/journal.pone.0152367. eCollection 2016.

Depression and Anxiety After Acute Myocardial Infarction Treated by Primary PCI

Free PMC article

Depression and Anxiety After Acute Myocardial Infarction Treated by Primary PCI

Petr Kala et al. PLoS One. .
Free PMC article


Aims: The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in sex.

Methods and results: The project enrolled 79 consecutive patients with the first AMI, aged <80 years (median 61 years, 21.5% of women) with a follow-up period of 12 months. Symptoms of depression or anxiety were measured using the Beck Depression Inventory II tests (BDI-II, cut-off value ≥14) and Self-Rating Anxiety Scale (SAS, cut-off ≥ 45) within 24 hours of pPCI, before the discharge, and in 3, 6 and 12 months). Results with the value p<0.05 were considered as statistically significant. The BDI-II positivity was highest within 24 hours after pPCI (21.5%) with a significant decline prior to the discharge (9.2%), but with a gradual increase in 3, 6 and 12 months (10.4%; 15.4%; 13.8% respectively). The incidence of anxiety showed a relatively similar trend: 8.9% after pPCI, and 4.5%, 10.8% and 6.2% in further follow-up.

Conclusions: Patients with STEMI treated by primary PCI have relatively low overall prevalence of symptoms of depression and anxiety. A significant decrease in mental stress was observed before discharge from the hospital, but in a period of one year after pPCI, prevalence of both symptoms was gradually increasing, which should be given medical attention.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.


Fig 1
Fig 1. Prevalence of depression and anxiety symptoms in the course of 1 year after PCI.
Fig 2
Fig 2. Changes of sleep in the course of 1 year after PCI.
Fig 3
Fig 3. Loss of interest in sex in the course of 1 year after PCI.

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The authors received no specific funding for this work.