Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2016 Apr 13;11(4):e0152367.
doi: 10.1371/journal.pone.0152367. eCollection 2016.

Depression and Anxiety After Acute Myocardial Infarction Treated by Primary PCI

Affiliations
Free PMC article

Depression and Anxiety After Acute Myocardial Infarction Treated by Primary PCI

Petr Kala et al. PLoS One. .
Free PMC article

Abstract

Aims: The main objective of the study was to find out prevalence of depression and anxiety symptoms in the population of patients with AMI with ST-segment elevation (STEMI), treated with primary PCI (pPCI). Secondary target indicators included the incidence of sleep disorders and loss of interest in sex.

Methods and results: The project enrolled 79 consecutive patients with the first AMI, aged <80 years (median 61 years, 21.5% of women) with a follow-up period of 12 months. Symptoms of depression or anxiety were measured using the Beck Depression Inventory II tests (BDI-II, cut-off value ≥14) and Self-Rating Anxiety Scale (SAS, cut-off ≥ 45) within 24 hours of pPCI, before the discharge, and in 3, 6 and 12 months). Results with the value p<0.05 were considered as statistically significant. The BDI-II positivity was highest within 24 hours after pPCI (21.5%) with a significant decline prior to the discharge (9.2%), but with a gradual increase in 3, 6 and 12 months (10.4%; 15.4%; 13.8% respectively). The incidence of anxiety showed a relatively similar trend: 8.9% after pPCI, and 4.5%, 10.8% and 6.2% in further follow-up.

Conclusions: Patients with STEMI treated by primary PCI have relatively low overall prevalence of symptoms of depression and anxiety. A significant decrease in mental stress was observed before discharge from the hospital, but in a period of one year after pPCI, prevalence of both symptoms was gradually increasing, which should be given medical attention.

Conflict of interest statement

Competing Interests: The authors have declared that no competing interests exist.

Figures

Fig 1
Fig 1. Prevalence of depression and anxiety symptoms in the course of 1 year after PCI.
Fig 2
Fig 2. Changes of sleep in the course of 1 year after PCI.
Fig 3
Fig 3. Loss of interest in sex in the course of 1 year after PCI.

Similar articles

See all similar articles

Cited by 9 articles

See all "Cited by" articles

References

    1. Thombs BD, Bass EB, Ford DE, Stewart KJ, Tsilidis KK, Patel U, et al. Prevalence of depression in survivors of acute myocardial infarction. J Gen Intern Med. 2006;21: 30–38. 10.1111/j.1525-1497.2005.00269.x - DOI - PMC - PubMed
    1. Lane D. The prevalence and persistence of depression and anxiety following myocardial infarction. Carroll D, Ring C, Beevers DG, Lip GYH, editors. Br J Health Psychol. 2002;7: 11 - PubMed
    1. Havik OE, Maeland JG. Patterns of emotional reactions after a myocardial infarction. J Psychosom Res. 1990;34: 271–285. - PubMed
    1. Thompson DR, Webster RA, Cordle CJ, Sutton TW. Specific sources and patterns of anxiety in male patients with first myocardial infarction. Br J Med Psychol. 1987;60 (Pt 4): 343–348. - PubMed
    1. Höschl C, Libiger J, Švestka J, editors. Psychiatrie. 1. vyd. Praha: Tigis; 2002.

MeSH terms

Grant support

The authors received no specific funding for this work.
Feedback