The Plot Thickens: Diet Microbe Interactions May Modulate Thrombosis Risk

Cell Metab. 2016 Apr 12;23(4):573-5. doi: 10.1016/j.cmet.2016.03.017.


Thrombosis plays an important role in cardiovascular disease (CVD). Platelet activation is an essential step in the genesis and propagation of atherothrombotic complications. In a recent publication, Zhu and colleagues report that gut microbe-derived TMAO enhances platelet responsiveness and thrombosis, providing a novel mechanistic connection between microbes and CVD (Zhu et al., 2016).

Publication types

  • Comment

MeSH terms

  • Cardiovascular Diseases
  • Diet*
  • Humans
  • Microbial Interactions
  • Thrombosis*