The Fiber Gap and the Disappearing Gut Microbiome: Implications for Human Nutrition

Trends Endocrinol Metab. 2016 May;27(5):239-242. doi: 10.1016/j.tem.2016.03.001. Epub 2016 Apr 11.


Increasing evidence indicates that modern lifestyle, and specifically a Western diet, has led to a substantial depletion of the human gut microbiome. This loss is implicated in the rampant increase of chronic diseases, providing an incentive to fundamentally transform human nutrition towards being more holistic and microbiome-focused.

Keywords: dietary fiber; gut microbiome; microbial diversity; microbiome conservation; microbiome depletion.

MeSH terms

  • Dietary Fiber / microbiology*
  • Gastrointestinal Microbiome / physiology*
  • Gastrointestinal Tract / metabolism
  • Gastrointestinal Tract / microbiology*
  • Humans
  • Nutritional Status


  • Dietary Fiber