Rabies direct fluorescent antibody test does not inactivate rabies or eastern equine encephalitis viruses

Abstract

An examination using the routine rabies direct fluorescent antibody test was performed on rabies or Eastern equine encephalitis positive mammalian brain tissue to assess inactivation of the virus. Neither virus was inactivated with acetone fixation nor the routine test, thus laboratory employees should treat all samples as rabies and when appropriate Eastern equine encephalitis positive throughout the whole procedure.

Keywords: Acetone; Diagnosis; Direct fluorescent antibody test; Eastern equine encephalitis; Inactivation; Rabies.