Pulmonary Mycobacterium abscessus Infection in a Patient with Triple A Syndrome

J Trop Pediatr. 2016 Aug;62(4):324-7. doi: 10.1093/tropej/fmv104. Epub 2016 Apr 14.

Abstract

Gastroesophageal disorders such as achalasia can be associated with pulmonary disorders because of non-tuberculous mycobacteria, frequently masquerading as aspiration pneumonia. The optimal therapeutic regimen and duration of treatment for non-tuberculous mycobacteria lung disease is not well established. Here, we present an 11 year old male patient with Mycobacterium abscessus pulmonary disease and underlying triple A syndrome, who was successfully treated with 2 months of imipenem, amikacin, clarithromycin and continued for long-term antibiotic treatment.

Keywords: Mycobacterium abscessus; achalasia; aspiration pneumonia; non-tuberculous mycobacteria.

Publication types

  • Case Reports

MeSH terms

  • Adrenal Insufficiency / complications*
  • Amikacin / therapeutic use
  • Anti-Bacterial Agents / therapeutic use*
  • Child
  • Clarithromycin / therapeutic use
  • Esophageal Achalasia / complications*
  • Humans
  • Imipenem / therapeutic use
  • Male
  • Mycobacterium Infections, Nontuberculous / drug therapy*
  • Mycobacterium Infections, Nontuberculous / pathology
  • Nontuberculous Mycobacteria / isolation & purification*
  • Treatment Outcome

Substances

  • Anti-Bacterial Agents
  • Imipenem
  • Amikacin
  • Clarithromycin

Supplementary concepts

  • Achalasia Addisonianism Alacrimia syndrome