A Framework for Adapted Nutritional Therapy for Children With Cancer in Low- and Middle-Income Countries: A Report From the SIOP PODC Nutrition Working Group

Pediatr Blood Cancer. 2016 Aug;63(8):1339-48. doi: 10.1002/pbc.26016. Epub 2016 Apr 15.


The utilization of adapted regimens for the treatment of pediatric malignancies has greatly improved clinical outcomes for children receiving treatment in low- and middle-income countries (LMIC). Nutritional depletion has been associated with poorer outcomes, increased abandonment of therapy, and treatment-related toxicities. Surveys have found that nutritional intervention is not incorporated routinely into supportive care regimens. Establishing nutritional programs based upon institutional resources may facilitate the incorporation of nutritional therapy into clinical care in a way that is feasible in all settings. We present a framework for establishing and monitoring of nutritional care based on the infrastructure of institutions in LMIC.

Keywords: adapted guidelines; international outreach; low- and middle-income countries; nutrition; nutritional status.

MeSH terms

  • Child
  • Developing Countries
  • Humans
  • Neoplasms / diet therapy*
  • Neoplasms / therapy
  • Nutrition Policy*
  • Nutrition Therapy / methods*
  • Nutritional Status*
  • Nutritional Support / methods*
  • Poverty