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. 2016 May;89(5):973-975.
doi: 10.1016/j.kint.2016.03.003.

In Experimental Chronic Kidney Disease or Cancer, Parathyroid Hormone Is a Novel Mediator of Cachexia

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In Experimental Chronic Kidney Disease or Cancer, Parathyroid Hormone Is a Novel Mediator of Cachexia

Christina M Wyatt et al. Kidney Int. .

Abstract

Hyperparathyroidism plays a central role in the disordered bone mineral metabolism of chronic kidney disease, and has been associated with increased cardiovascular morbidity and mortality in that setting. A recent study suggests a novel role for parathyroid hormone and its receptor in muscle wasting and cachexia occurring in advanced chronic kidney disease.

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