[Parathyromatosis: An uncommon cause of recurrent hyperparathyroidism]

Rev Med Interne. 2017 Jan;38(1):61-64. doi: 10.1016/j.revmed.2016.03.005. Epub 2016 Apr 12.
[Article in French]

Abstract

Introduction: Parathyromatosis is a rare cause of recurrent hyperparathyroidism. It results from hyperfunctioning parathyroid tissue scattered throughout the thyroid bed region.

Case report: A 51-year-old man with a history of parathyroidectomy, presented 18 years later with recurrent primary hyperparathyroidism. Surgical exploration identified a single parathyroid gland. The act was completed by a central compartment dissection and ipsilateral lobectomy. The patient was free of recurrence after a one-year follow-up.

Conclusion: Parathyromatosis a rare cause of recurrent hyperparathyroidism. Its management is challenging. Extensive surgery is required with clearance of the central neck compartment and homolateral lobectomy. Medical therapy could be used to decrease parathormone level in recurrent parathyromatosis.

Keywords: Chirurgie; Glande parathyroïde; Hyperparathyroidism; Hyperparathyroïdie primaire; Parathyroid glands; Parathyroidectomy; Parathyroïdectomie; Surgery.

Publication types

  • Case Reports

MeSH terms

  • Humans
  • Hyperparathyroidism, Secondary / etiology*
  • Hyperparathyroidism, Secondary / pathology
  • Hyperplasia / complications
  • Male
  • Middle Aged
  • Parathyroid Glands / metabolism
  • Parathyroid Glands / pathology*
  • Parathyroid Hormone / metabolism
  • Recurrence

Substances

  • Parathyroid Hormone