Pre-cannulation lung biopsy shortens ECMO course

Pediatr Surg Int. 2016 Jul;32(7):713-6. doi: 10.1007/s00383-016-3890-5. Epub 2016 Apr 16.


We describe the clinical course of an infant with respiratory failure who underwent lung biopsy prior to cannulation for undergoing extracorporeal membrane oxygenation (ECMO). Pathology revealed alveolar capillary dysplasia, and ECMO was discontinued. Rapid diagnosis allowed for closure and saved resources. We recommend considering early biopsy in infants with atypical pulmonary hypertension.

Keywords: Alveolar capillary dysplasia; Lung biopsy; Neonate; Pulmonary hypertension.

Publication types

  • Case Reports

MeSH terms

  • Biopsy / methods*
  • Catheterization / methods*
  • Extracorporeal Membrane Oxygenation / methods*
  • Humans
  • Infant, Newborn
  • Lung / pathology*
  • Male
  • Persistent Fetal Circulation Syndrome / complications
  • Persistent Fetal Circulation Syndrome / therapy*
  • Pulmonary Alveoli / abnormalities*
  • Respiratory Insufficiency / etiology
  • Respiratory Insufficiency / therapy*

Supplementary concepts

  • Alveolar capillary dysplasia