[Spondylarthropathies: conventional treatments and anti-TNF]

Rev Med Suisse. 2016 Mar 9;12(509):507-8, 510-1.
[Article in French]


Non-steroidal anti-inflammatory drugs (NSAID) are the first line treatment for spondylarthritis. NSAIDs are effective when used continuously or on demand, in short or long-term use. An effect on radiologic progression of the spine is still controversial. However, physicians have to be aware of potential cardiovascular, renal or gastro-intestinal secondary effects when prescribing NSAIDs. DMARDs like methotrexate or systemic corticosteroids are generally not recommended for the treatment of spondylarthritis. After NSAIDs failure, a TNF inhibitor can be used. 5 anti-TNF are available in Switzerland and they are all effective in this disease. Before starting an anti-TNF treatment, a screening is mandatory. Patients treated with an anti-TNF must be followed regularly.

Publication types

  • English Abstract

MeSH terms

  • Anti-Inflammatory Agents, Non-Steroidal / therapeutic use*
  • Antirheumatic Agents / therapeutic use*
  • Humans
  • Meta-Analysis as Topic
  • Randomized Controlled Trials as Topic
  • Spondylarthropathies / drug therapy*
  • Switzerland
  • Time Factors
  • Treatment Outcome
  • Tumor Necrosis Factor-alpha / antagonists & inhibitors*


  • Anti-Inflammatory Agents, Non-Steroidal
  • Antirheumatic Agents
  • Tumor Necrosis Factor-alpha