Spontaneous partial loss of the OT-I transgene

Nat Immunol. 2016 May;17(5):471. doi: 10.1038/ni.3411.

Authors

Gretchen Harms Pritchard¹, Eric W Cross², Marjorie Strobel³, Stephen C Jameson⁴, Ross M Kedl², Kristin A Hogquist⁴, Christopher A Hunter¹

Affiliations

¹ Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
² Department of Immunology and Microbiology, University of Colorado Denver, School of Medicine, Aurora, Colorado, USA.
³ Animal Resources, The Jackson Laboratory, Bar Harbor, Maine, USA.
⁴ Center for Immunology, Department of Lab Medicine &Pathology, University of Minnesota, Minneapolis, Minnesota, USA.

PMID: 27092794
PMCID: PMC5073790
DOI: 10.1038/ni.3411

No abstract available

Publication types

Letter

MeSH terms

Amino Acid Sequence
Animals
CD8-Positive T-Lymphocytes / immunology*
CD8-Positive T-Lymphocytes / metabolism
Flow Cytometry
H-2 Antigens / immunology*
H-2 Antigens / metabolism
Mice, Transgenic
Ovalbumin / genetics
Ovalbumin / immunology*
Ovalbumin / metabolism
Peptide Fragments / genetics
Peptide Fragments / immunology
Peptide Fragments / metabolism
Polymerase Chain Reaction
Receptors, Antigen, T-Cell, alpha-beta / genetics
Receptors, Antigen, T-Cell, alpha-beta / immunology*
Receptors, Antigen, T-Cell, alpha-beta / metabolism
T-Cell Antigen Receptor Specificity / immunology

Substances

H-2 Antigens
H-2Kb protein, mouse
OVA-8
Peptide Fragments
Receptors, Antigen, T-Cell, alpha-beta
Ovalbumin

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