Centromeres of a Different CAL-ibre

Ewelina Zasadzińska; Daniel R Foltz

doi:10.1016/j.devcel.2016.04.006

Centromeres of a Different CAL-ibre

Dev Cell. 2016 Apr 18;37(2):105-6. doi: 10.1016/j.devcel.2016.04.006.

Authors

Ewelina Zasadzińska¹, Daniel R Foltz²

Affiliations

¹ Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA.
² Department of Biochemistry and Molecular Genetics, University of Virginia School of Medicine, Charlottesville, VA 22908, USA; Department of Biochemistry and Molecular Genetics, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA; Robert H. Lurie Comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL 60611, USA. Electronic address: dfoltz@northwestern.edu.

PMID: 27093076
DOI: 10.1016/j.devcel.2016.04.006

Abstract

Centromeres of higher eukaryotes are defined by the epigenetic inheritance of the centromere-specific CENP-A nucleosome. Reporting in Developmental Cell, Rosin and Mellone (2016) show that co-evolution of the CENP-A histone variant and its chaperone CAL1 accounts for species incompatibility between centromeric histones in Drosophila.

Publication types

Comment

MeSH terms

Animals
Centromere*
Drosophila
Drosophila Proteins
Histones*
Nucleosomes

Substances

Drosophila Proteins
Histones
Nucleosomes

Grants and funding

R01 GM111907/GM/NIGMS NIH HHS/United States