Cardiac Sarcoidosis Masked by Malignant Lymphoma

Can J Cardiol. 2016 Aug;32(8):1039.e11-3. doi: 10.1016/j.cjca.2015.09.014. Epub 2015 Sep 26.

Abstract

There is an association between sarcoidosis and lymphoma, termed "sarcoidosis-lymphoma syndrome." Sarcoidosis is generally detected before lymphoma, but it could present after or even concurrently with the diagnosis of lymphoma. We describe a patient presenting with ventricular tachycardia and lymphadenopathy. A diagnosis of Hodgkin lymphoma was made histologically. The patient responded to treatment, but had persistent (18)F-fluoro-deoxyglucose uptake in the lymph nodes and heart on follow-up positron emission tomography. Second biopsies of lymph node and endomyocardial both confirmed sarcoidosis. This finding suggests that we should maintain a high degree of suspicion for cardiac sarcoidosis in lymphoma patients.

Publication types

  • Case Reports

MeSH terms

  • Cardiomyopathies / complications
  • Cardiomyopathies / diagnosis*
  • Hodgkin Disease / complications
  • Hodgkin Disease / diagnosis*
  • Humans
  • Lymph Nodes / pathology
  • Male
  • Middle Aged
  • Myocardium / pathology
  • Positron Emission Tomography Computed Tomography
  • Sarcoidosis / complications
  • Sarcoidosis / diagnosis*