From Child-Pugh to Model for End-Stage Liver Disease: Deciding Who Needs a Liver Transplant

Sheela S Reddy; Jesse M Civan

doi:10.1016/j.mcna.2015.12.002

From Child-Pugh to Model for End-Stage Liver Disease: Deciding Who Needs a Liver Transplant

Med Clin North Am. 2016 May;100(3):449-64. doi: 10.1016/j.mcna.2015.12.002. Epub 2016 Mar 17.

Authors

Sheela S Reddy¹, Jesse M Civan²

Affiliations

¹ Division of Gastroenterology & Hepatology, Department of Medicine, Thomas Jefferson University, Suite 480 Main Building, 132 South 10th Street, Philadelphia, PA 19107, USA.
² Division of Gastroenterology & Hepatology, Department of Medicine, Thomas Jefferson University, Suite 480 Main Building, 132 South 10th Street, Philadelphia, PA 19107, USA. Electronic address: Jesse.Civan@jefferson.edu.

PMID: 27095638
DOI: 10.1016/j.mcna.2015.12.002

Abstract

This article reviews the historical evolution of the liver transplant organ allocation policy and the indications/contraindications for liver transplant, and provides an overview of the liver transplant evaluation process. The article is intended to help internists determine whether and when referral to a liver transplant center is indicated, and to help internists to counsel patients whose initial evaluation at a transplant center is pending.

Keywords: Cirrhosis; Hepatocellular carcinoma; Liver transplantation; MELD score; Organ allocation.

Publication types

Review

MeSH terms

Carcinoma, Hepatocellular / classification
Carcinoma, Hepatocellular / diagnosis
Carcinoma, Hepatocellular / surgery
End Stage Liver Disease / classification
End Stage Liver Disease / diagnosis
End Stage Liver Disease / surgery*
Hepatic Encephalopathy / classification
Hepatic Encephalopathy / diagnosis
Hepatic Encephalopathy / surgery*
Humans
Liver Cirrhosis / classification
Liver Cirrhosis / diagnosis
Liver Cirrhosis / surgery*
Liver Failure, Acute / classification
Liver Failure, Acute / diagnosis*
Liver Failure, Acute / surgery*
Liver Function Tests
Liver Neoplasms / classification
Liver Neoplasms / diagnosis
Liver Neoplasms / surgery
Liver Transplantation* / statistics & numerical data
Organ Dysfunction Scores*
Patient Transfer
Prognosis
Registries
Utilization Review