MRI of "diffusion" in the human brain: new results using a modified CE-FAST sequence

Magn Reson Med. 1989 Mar;9(3):423-9. doi: 10.1002/mrm.1910090316.


"Diffusion-weighted"MRI in the normal human brain and in a patient with a cerebral metastasis is demonstrated. The method employed was a modified CE-FAST sequence with imaging times of only 6-10 s using a conventional 1.5-T whole-body MRI system (Siemens Magnetom). As with previous phantom and animal studies, the use of strong gradients together with macroscopic motions in vivo causes unavoidable artifacts in diffusion-weighted images of the human brain. While these artifacts are shown to be considerably reduced by averaging of 8-16 images, the resulting diffusion contrast is compromised by unknown signal losses due to motion.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Aged
  • Brain / metabolism*
  • Brain Neoplasms / metabolism
  • Diffusion
  • Female
  • Humans
  • Image Enhancement / methods*
  • Magnetic Resonance Imaging / methods*