[Waist-hip ratio and perioperative bleeding in patients who underwent radical prostatectomy]

Rev Med Inst Mex Seguro Soc. May-Jun 2016;54(3):297-303.
[Article in Spanish]

Abstract

Background: Radical prostatectomy is associated with perioperative bleeding and multiple transfusions. Abdominal obesity is a perioperative risk factor. We suggest that the adipocytes have a protective effect in oncological patients undergoing radical prostatectomy. The aim was to evaluate the effect of waist-hip ratio (WHR) on the amount of bleeding and perioperative transfusion requirements in oncological patients undergoing radical prostatectomy.

Methods: We performed a cohort study in 156 patients. We had two groups: the control group (WHR<0.95) and the problem group (WHR≥0.95). Blood loss and fractions transfused during surgery and in the postoperative period were recorded. In the analysis of variables, for descriptive statistics we used measures of central tendency and dispersion. Inferential statistics was obtained by chi square, Student's t test, Mann-Whitney U and ANOVA. A p<0.05 was significant.

Results: We found significant differences in weight, body mass index, waist, WHR, perioperative bleeding, fractions transfused, permanence of the catheter, and hospital days.

Conclusions: Patients who underwent radical prostatectomy with a WHR≥0.95 had a magnitude of perioperative bleeding and transfusion requirements with a WHR<0.95.

Introducción: la prostatectomía radical se asocia con sangrado perioperatorio y múltiples transfusiones. La obesidad abdominal representa un factor de riesgo perioperatorio. Sugerimos un efecto protector del adipocito en pacientes oncológicos sometidos a prostatectomía radical. El objetivo fue evaluar el efecto del índice cintura-cadera (ICC) sobre la magnitud del sangrado y los requerimientos perioperatorios de transfusiones en pacientes oncológicos sometidos a prostatectomía radical. Métodos: estudio de cohorte en 156 pacientes. Se integraron dos grupos: el control (ICC < 0.95) y el problema (ICC > 0.95); se registraron la magnitud del sangrado y las fracciones transfundidas durante la cirugía y en el postoperatorio. Se utilizaron medidas de tendencia central y dispersión, así como chi cuadrada, t de Student, U de Mann-Whitney y ANOVA. Una p < 0.05 fue significativa. Resultados: encontramos diferencias significativas en el peso, índice de masa corporal, cintura, índice cintura-cadera, sangrado perioperatorio, fracciones transfundidas, permanencia de la sonda y días de hospitalización. Conclusión: los pacientes sometidos a prostatectomía radical con ICC ≥ 0.95 tuvieron un sangrado y requerimientos transfusionales perioperatorios menores que aquellos con un ICC < 0.95.

Keywords: Abdominal obesity; Bleeding; Prostatectomy; Waist-hip ratio.

Publication types

  • Clinical Trial

MeSH terms

  • Aged
  • Blood Loss, Surgical*
  • Blood Transfusion / statistics & numerical data
  • Humans
  • Longitudinal Studies
  • Male
  • Middle Aged
  • Obesity, Abdominal / complications*
  • Obesity, Abdominal / diagnosis
  • Postoperative Hemorrhage / etiology*
  • Postoperative Hemorrhage / therapy
  • Prospective Studies
  • Prostatectomy*
  • Protective Factors
  • Risk Factors
  • Waist-Hip Ratio*