Inflammatory facial acne during uncomplicated pregnancy and post-partum in adult women: a preliminary hospital-based prospective observational study of 35 cases from Taiwan

J Eur Acad Dermatol Venereol. 2016 Oct;30(10):1787-1789. doi: 10.1111/jdv.13667. Epub 2016 Apr 22.


Background: Pregnancy is associated with significant changes in hormones and metabolism which can also exert impact on the skin.

Objectives: The study was aimed to evaluate the facial acne severity during pregnancy and post-partum period and to identify risk factors for acne in pregnancy.

Methods: A hospital-based prospective study on pregnant women at age ≥18 years was conducted during their routine maternal examination. The severity of inflammatory facial acne was evaluated by the number of acne lesions and Global Acne Severity Scale, based on pictures taken at the three trimesters of pregnancy and post-partum period. Risk factors were identified by review of medical chart and questionnaires. Correlation with acne severity was statistically analysed.

Results: Thirty-five pregnant women were included in this study with ages ranging from 25 to 40 years. The average number of facial acne was highest in the second trimester. Primigravida, female gender and low birth weight for gestational age of the newborn were associated with higher numbers of facial acne in the second and third trimester in our series.

Conclusions: Further investigation on a larger population and the relevant hormone changes is required to confirm and explain our findings.

MeSH terms

  • Acne Vulgaris / complications*
  • Adult
  • Face
  • Female
  • Humans
  • Postpartum Period*
  • Pregnancy
  • Pregnancy Complications / physiopathology*
  • Prospective Studies
  • Risk Factors
  • Taiwan