HIV-Positive-to-HIV-Positive Liver Transplantation

Am J Transplant. 2016 Aug;16(8):2473-8. doi: 10.1111/ajt.13824. Epub 2016 Jun 7.


Most countries exclude human immunodeficiency virus (HIV)-positive patients from organ donation because of concerns regarding donor-derived HIV transmission. The Swiss Federal Act on Transplantation has allowed organ transplantation between HIV-positive donors and recipients since 2007. We report the successful liver transplantation from an HIV-positive donor to an HIV-positive recipient. Both donor and recipient had been treated for many years with antiretroviral therapy and harbored multidrug-resistant viruses. Five months after transplantation, HIV viremia remains undetectable. This observation supports the inclusion of appropriate HIV-positive donors for transplants specifically allocated to HIV-positive recipients.

Keywords: clinical research/practice; ethics and public policy; immune deficiency; infectious disease; patient safety.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Graft Survival / immunology*
  • HIV Infections / surgery*
  • HIV Infections / virology
  • HIV Seropositivity*
  • HIV-1 / immunology*
  • Humans
  • Liver Transplantation*
  • Male
  • Middle Aged
  • Prognosis
  • Tissue Donors / supply & distribution*
  • Tissue and Organ Procurement*