The avian-origin H3N2 canine influenza virus that recently emerged in the United States has limited replication in swine

Influenza Other Respir Viruses. 2016 Sep;10(5):429-32. doi: 10.1111/irv.12395. Epub 2016 May 18.

Abstract

Equine-origin H3N8 has circulated in dogs in the United States since 1999. A genetically and antigenically distinct avian-origin H3N2 canine influenza was detected in March of 2015 in Chicago, Illinois. Subsequent outbreaks were reported with over 1000 dogs in the Midwest affected followed by 23 additional states with detections within 5 months. The potential for canine-to-swine transmission was unknown. Experimental infection in pigs showed this virus does not replicate efficiently in swine.

Keywords: Avian influenza; H3N2 virus; canine influenza.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Animals
  • Birds
  • Chicago / epidemiology
  • Disease Outbreaks
  • Dog Diseases / virology*
  • Dogs / virology
  • Influenza A Virus, H3N2 Subtype / genetics
  • Influenza A Virus, H3N2 Subtype / isolation & purification
  • Influenza A Virus, H3N2 Subtype / physiology*
  • Influenza A Virus, H3N8 Subtype / genetics
  • Influenza A Virus, H3N8 Subtype / isolation & purification
  • Influenza in Birds / epidemiology
  • Influenza in Birds / virology*
  • Orthomyxoviridae Infections / epidemiology
  • Orthomyxoviridae Infections / transmission
  • Orthomyxoviridae Infections / veterinary*
  • Orthomyxoviridae Infections / virology
  • Phylogeny
  • Swine
  • Swine Diseases / virology*
  • United States / epidemiology
  • Virus Replication*

Associated data

  • GENBANK/KT002533
  • GENBANK/KT002540