Norovirus epidemics caused by new GII.2 chimera viruses in 2012-2014 in Japan

Infect Genet Evol. 2016 Aug;42:49-52. doi: 10.1016/j.meegid.2016.04.026. Epub 2016 Apr 22.

Abstract

The new GII.2 variant collected from May 2012-March 2014 consisted of GII.15 and GII.2 genomes, in which the putative recombination points found in the boundary region between ORF1 and ORF2. These findings suggested that the swapping of structural and non-structural proteins is a common mechanism for generating new epidemic variants in nature.

Keywords: GII.2; New chimera virus; Norovirus.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Caliciviridae Infections / epidemiology*
  • Caliciviridae Infections / virology
  • Disease Outbreaks*
  • Epidemiological Monitoring
  • Feces / virology
  • Gastroenteritis / epidemiology*
  • Gastroenteritis / virology
  • Genotype
  • Humans
  • Japan / epidemiology
  • Mosaicism*
  • Norovirus / genetics*
  • Norovirus / pathogenicity
  • Phylogeny*
  • Reassortant Viruses / genetics*
  • Reassortant Viruses / pathogenicity
  • Recombination, Genetic
  • Retrospective Studies