LVIS Stent Versus Enterprise Stent for the Treatment of Unruptured Intracranial Aneurysms

World Neurosurg. 2016 Jul;91:365-70. doi: 10.1016/j.wneu.2016.04.057. Epub 2016 Apr 22.


Objective: This retrospective study compared clinical and angiographic outcomes between LVIS and Enterprise stents.

Materials and methods: From November 2014 to December 2015, total 190 patients with 208 unruptured intracranial aneurysms were coiled assisted by LVIS and Enterprise stents. Procedure-related complications, clinical outcomes, and angiographic results were analyzed retrospectively.

Results: A total of 92 patients with 96 aneurysms received LVIS stents and 98 patients with 112 aneurysms were treated with Enterprise stents. Procedure-related complications occurred in 10.9% of patients (2 hemorrhagic events and 8 thromboembolic events) in the LVIS stents group whereas 16.3% (1 hemorrhage, 1 mass effect, and 14 thromboembolic events) in the Enterprise stents group. No statistical significant differences in thromboembolic (P = 0.263), hemorrhagic complications (P = 0.611), and favorable clinical outcomes (modified Rankin Scores of 0-2) (P = 0.379) were found between 2 groups. A greater initial complete or near-complete obliteration was found in the LVIS stents group compared with the Enterprise stents group (96.9% vs. 88.4%, P = 0.034). Larger aneurysm size (P = 0.048) was an independent predictor of procedure-related complications in univariate analysis.

Conclusions: Compared with Enterprise stents, LVIS stents may achieve greater complete or near-complete occlusion rate. There was no significant difference in procedural-related complications and clinical outcomes between LVIS and Enterprise stents.

Keywords: Clinical outcomes; Endovascular embolization; Enterprise stents; Intracranial aneurysms; LVIS stents.

Publication types

  • Comparative Study

MeSH terms

  • Cerebral Hemorrhage / prevention & control
  • Embolization, Therapeutic / instrumentation
  • Embolization, Therapeutic / methods
  • Endovascular Procedures / methods
  • Female
  • Humans
  • Intracranial Aneurysm / therapy*
  • Ischemic Attack, Transient / etiology
  • Male
  • Middle Aged
  • Postoperative Complications / etiology
  • Retrospective Studies
  • Stents*
  • Stroke / etiology
  • Thromboembolism / etiology
  • Treatment Outcome