Continuous Renal Replacement Therapy for the Management of Acid-Base and Electrolyte Imbalances in Acute Kidney Injury

Adv Chronic Kidney Dis. 2016 May;23(3):203-10. doi: 10.1053/j.ackd.2016.02.005.

Abstract

Continuous renal replacement therapy (CRRT) is used to manage electrolyte and acid-base imbalances in critically ill patients with acute kidney injury. Although a standard solution and prescription is acceptable in most clinical circumstances, specific disorders may require a tailored approach such as adjusting fluid composition, regulating CRRT dose, and using separate intravenous infusions to mitigate and correct these disturbances. Errors in fluid prescription, compounding, or delivery can be rapidly fatal. This article provides an overview of the principles of acid-base and electrolyte management using CRRT.

Keywords: Acidosis; Alkalosis; CRRT; Hyperkalemia; Hyponatremia.

Publication types

  • Review

MeSH terms

  • Acid-Base Imbalance / complications
  • Acid-Base Imbalance / therapy*
  • Acidosis / complications
  • Acidosis / therapy
  • Acute Kidney Injury / complications
  • Acute Kidney Injury / therapy*
  • Alkalosis / complications
  • Alkalosis / therapy
  • Critical Care
  • Critical Illness
  • Humans
  • Hyperkalemia / complications
  • Hyperkalemia / therapy
  • Hyponatremia / complications
  • Hyponatremia / therapy
  • Renal Replacement Therapy / methods*
  • Water-Electrolyte Imbalance / complications
  • Water-Electrolyte Imbalance / therapy*