Catalytic Conversion of Alcohols into Carboxylic Acid Salts in Water: Scope, Recycling, and Mechanistic Insights

Abstract

The catalytic conversion of alcohols into carboxylic acid salts in water was performed in the presence of ruthenium complexes supported by aliphatic PNP pincer ligands preformed or formed in situ. High activity toward a wide substrate scope was achieved with turnover number values of up to 4000. The air-stable catalytic system can be recycled by using toluene as a catalyst-immobilizing phase; the activity is maintained after five consecutive runs. Finally, mechanistic studies allowed some fundamental aspects related to water activation to be unveiled and to the mechanism postulated.

Keywords: carboxylic acid; green chemistry; pincer ligands; reaction mechanisms; ruthenium.