Development and validation of the Patient Benefit Index for the dermatocosmetic treatment of aged skin

Arch Dermatol Res. 2016 Jul;308(5):319-24. doi: 10.1007/s00403-016-1648-5. Epub 2016 Apr 27.


This study aimed to develop and validate an instrument for the assessment of patient-relevant benefit in dermatocosmetic treatment, i.e., skin care, of aged skin. Based on an open item collection with 33 elderly persons, items on patient-relevant treatment goals were collected. An expert panel selected 20 items to be most relevant and feasible for the questionnaire named Patient Benefit Index for Aged Skin (PBI-AS). The instrument, which assesses goal importance and achievement, was tested in a cognitive debriefing and validated in a longitudinal study (n = 80) along with the Dry Skin Area and Severity Index (DASI) and the Dermatology Quality of Life Index (DLQI) as convergent validation criteria. The cognitive debriefing showed the good practicability and feasibility of the instrument. Significant correlation with change in DASI (r = -0.527; p < 0.001) supports convergent validity of the PBI-AS. By contrast, correlation with DLQI was poor, indicating the different constructs. The PBI-AS is a valid and feasible tool for the patient-centered assessment of dermatocosmetic treatment benefit in aged skin.

Keywords: Aged skin; Dermatocosmetic treatment; Patient-relevant benefit; Quality of life; Validation.

Publication types

  • Validation Study

MeSH terms

  • Aged
  • Aged, 80 and over
  • Feasibility Studies
  • Female
  • Humans
  • Longitudinal Studies
  • Male
  • Patient Outcome Assessment*
  • Patient Satisfaction*
  • Quality of Life
  • Skin Aging*
  • Skin Care* / statistics & numerical data
  • Surveys and Questionnaires