Alterations of atrial repolarization after tricyclic antidepressant drugs absorption

Acta Cardiol. 1989;44(1):15-8.


We describe a case of voluntary intoxication with tricyclic antidepressant drugs: initial electrocardiogram showed alterations of atrial repolarization (Ta segment) which were more pronounced than usual ST-T alterations. Evolution was uneventful (and repolarization normalized). Tricyclic antidepressant drugs absorption can lead to Ta segment alterations, which may be a useful clue in the differential diagnosis of drugs intoxication.

Publication types

  • Case Reports

MeSH terms

  • Antidepressive Agents, Tricyclic / pharmacokinetics*
  • Atrial Function
  • Electrocardiography*
  • Electrophysiology
  • Female
  • Heart Atria / drug effects*
  • Humans
  • Middle Aged


  • Antidepressive Agents, Tricyclic