Fibroblast Senescence as a Therapeutic Target of Myocardial Fibrosis: Beyond Spironolactone?

J Am Coll Cardiol. 2016 May 3;67(17):2029-31. doi: 10.1016/j.jacc.2016.02.048.

¹ Department of Cardiovascular Medicine, Humanitas Research Hospital and Humanitas University, Rozzano, Milan, Italy; Institute of Genetics and Biomedical Research National Research Council of Italy, Rozzano, Milan, Italy. Electronic address: gianluigi.condorelli@hunimed.eu.
² Department of Biomedical, Biotechnological and Translational Sciences, University of Parma, Parma, Italy.
³ Department of Cardiovascular Medicine, Humanitas Research Hospital and Humanitas University, Rozzano, Milan, Italy.

No abstract available

Keywords: aging; fibroblast; gene expression; heart failure; tumor suppressor genes.

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