Linear scleroderma with prominent multiple lymphadenopathy followed by the development of polymyositis: A case report and review of published work

Abstract

Localized scleroderma is an inflammatory disorder affecting the skin and underlying tissues, a certain subset of which develops other autoimmune diseases on the basis of a prominent autoimmune background. We here report a unique case of linear scleroderma presenting with a sclerotic plaque on the left thigh, multiple lymphadenopathy in bilateral inguinal and para-aortic lymph nodes, and hepatosplenomegaly, who later developed polymyositis. We describe the detailed disease course of our case and discuss the clinical significance of multiple lymphadenopathy in localized scleroderma based on a review of published work.

Keywords: hepatosplenomegaly; immune abnormality; linear scleroderma; lymphadenopathy; polymyositis.