Patient-Reported Outcomes in Rheumatoid Arthritis

Rheum Dis Clin North Am. 2016 May;42(2):219-37. doi: 10.1016/j.rdc.2016.01.010. Epub 2016 Mar 17.


Patient-reported outcomes (PROs) and their measures have a long and important history for determining the status and treatment of patients with rheumatoid arthritis (RA). This article describes the history and evolution of PROs for RA and the current state of the field, with key examples of accepted and widely used measures, and offers some reflection on the roles of PROs for the study and management of RA.

Keywords: Health domains; Patient-reported outcomes; Questionnaires; Rheumatoid arthritis.

Publication types

  • Review

MeSH terms

  • Activities of Daily Living*
  • Arthralgia / etiology
  • Arthralgia / physiopathology*
  • Arthritis, Rheumatoid / complications
  • Arthritis, Rheumatoid / physiopathology*
  • Arthritis, Rheumatoid / psychology
  • Cognitive Dysfunction / etiology
  • Cognitive Dysfunction / psychology
  • Depression / etiology
  • Depression / psychology
  • Fatigue / etiology
  • Fatigue / physiopathology*
  • Humans
  • Patient Reported Outcome Measures*
  • Quality Indicators, Health Care
  • Quality of Life
  • Severity of Illness Index
  • Sleep Wake Disorders / etiology
  • Sleep Wake Disorders / physiopathology*