Ultrasmall Biocompatible WO3- x Nanodots for Multi-Modality Imaging and Combined Therapy of Cancers

Adv Mater. 2016 Jul;28(25):5072-9. doi: 10.1002/adma.201506428. Epub 2016 May 2.


Ultrasmall biocompatible WO3 - x nanodots with an outstanding X-ray radiation sensitization effect are prepared, and demonstrated to be applicable for multi-modality tumor imaging through computed tomography and photoacoustic imaging (PAI), and effective cancer treatment combining both photothermal therapy and radiation therapy.

Keywords: combined tumor therapy; multi-modality imaging; radiation sensitization; tungsten oxide; ultrasmall nanodots.

MeSH terms

  • Humans
  • Multimodal Imaging
  • Nanostructures
  • Neoplasms
  • Phototherapy
  • Tomography, X-Ray Computed
  • Tungsten / chemistry*


  • Tungsten