Kinetics of serum glutamate dehydrogenase during short-term alcohol withdrawal

J Weill; F Schellenberg; A M Le Goff

doi:10.1016/0009-8981(89)90095-8

Kinetics of serum glutamate dehydrogenase during short-term alcohol withdrawal

Clin Chim Acta. 1989 Feb 22;179(3):323-6. doi: 10.1016/0009-8981(89)90095-8.

Authors

J Weill¹, F Schellenberg, A M Le Goff

Affiliation

¹ Laboratoire de Biochimie, Centre Hospitalier Régional Universitaire Trousseau, Tours, France.

PMID: 2714005
DOI: 10.1016/0009-8981(89)90095-8

Abstract

The behavior of serum glutamate dehydrogenase after alcohol withdrawal was studied in 64 alcoholics admitted to a detoxification center. The enzyme activity decreased in 57 patients by a median of -35.8 percent in 24 h. Thus, the decrease of serum glutamate dehydrogenase after 24 h of ethanol abstinence can serve as a test of alcohol abuse.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Adult
Alcoholism / blood
Alcoholism / enzymology*
Female
Glutamate Dehydrogenase / metabolism*
Humans
Male
Middle Aged
Temperance

Substances

Glutamate Dehydrogenase