New Evidence of Long-lasting Persistence of Ebola Virus Genetic Material in Semen of Survivors

J Infect Dis. 2016 Nov 15;214(10):1475-1476. doi: 10.1093/infdis/jiw078. Epub 2016 May 3.


Ninety-eight semen specimens were obtained for Ebola virus (EBOV) RNA screening from 68 men in Guinea during the convalescent phase of EBOV infection. Ten samples from 8 men were positive for EBOV up to 9 months after onset of the disease, with decreasing trends in the proportion of positive samples and the level of viral RNA. Safe sex practices should be observed after discharge from treatment centers.

Keywords: Ebola virus; Guinea; outbreak; semen; survivors; virus persistence.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adult
  • Ebolavirus / genetics
  • Ebolavirus / isolation & purification*
  • Female
  • Follow-Up Studies
  • Guinea
  • Hemorrhagic Fever, Ebola / virology*
  • Humans
  • Male
  • Middle Aged
  • Pregnancy
  • RNA, Viral / analysis*
  • RNA, Viral / genetics
  • Semen / virology*
  • Time Factors
  • Young Adult


  • RNA, Viral