Brain protection during cephalosomatic anastomosis

Surgery. 2016 Jul;160(1):5-10. doi: 10.1016/j.surg.2016.01.026. Epub 2016 Apr 30.

Abstract

Cephalosomatic anastomosis requires neuroprotective techniques, such as deep hypothermia, to preserve brain activity. Despite the failure of pharmacologic neuroprotection, new strategies, including ischemic pre- and postconitioning and the use of Perftoran, have to be explored to complement hypothermia. This article summarizes the field of brain protection during CSA and these promising strategies.

Publication types

  • Review

MeSH terms

  • Animals
  • Brain / blood supply*
  • Brain Tissue Transplantation / methods*
  • Fluorocarbons / therapeutic use
  • Humans
  • Hypothermia, Induced
  • Ischemic Preconditioning
  • Neuroprotective Agents / therapeutic use

Substances

  • Fluorocarbons
  • Neuroprotective Agents
  • perftoran