Overview of Common Sleep Disorders and Intersection with Dermatologic Conditions

Int J Mol Sci. 2016 Apr 30;17(5):654. doi: 10.3390/ijms17050654.


Sleep disorders are very common, often under-recognized and therefore undertreated, are associated with a myriad of medical conditions and could lead to significant impairment of quality of life. This review provides an up-to-date synopsis of common sleep disorders encompassing insufficient sleep syndrome, insomnia, circadian rhythm disorders and obstructive sleep apnea with a brief overview of epidemiology, screening, diagnostic testing and treatment. We also emphasize the emerging area of the intersection of sleep disorders and dermatologic conditions and present compelling data regarding underlying mechanisms including sleep dysfunction in relation to disorders of skin inflammation, aging and skin cancer.

Keywords: insufficient sleep; sleep and skin disorders; sleep disorders.

Publication types

  • Review

MeSH terms

  • Eczema / complications
  • Eczema / pathology
  • Humans
  • Psoriasis / complications
  • Psoriasis / pathology
  • Skin Aging
  • Skin Diseases / complications
  • Skin Diseases / pathology*
  • Skin Neoplasms / complications
  • Skin Neoplasms / pathology
  • Sleep Apnea, Obstructive / complications
  • Sleep Apnea, Obstructive / pathology
  • Sleep Initiation and Maintenance Disorders / complications
  • Sleep Initiation and Maintenance Disorders / pathology
  • Sleep Wake Disorders / complications
  • Sleep Wake Disorders / pathology*