readat: An R package for reading and working with SomaLogic ADAT files

BMC Bioinformatics. 2016 May 4;17(1):201. doi: 10.1186/s12859-016-1007-8.

Abstract

Background: SomaLogic's SOMAscan™ assay platform allows the analysis of the relative abundance of over 1300 proteins directly from biological matrices such as blood plasma and serum. The data resulting from the assay is provided in a proprietary text-based format not easily imported into R.

Results: readat is an R package for working with the SomaLogic ADAT file format. It provides functionality for importing, transforming and annotating data from these files. The package is free, open source, and available on Bioconductor and Bitbucket.

Conclusions: readat integrates into both Bioconductor and traditional R workflows, rendering it easy to make use of ADAT files.

Keywords: ADAT; Bioconductor; Dynamic range; Proteomics; R; Software; SomaLogic.

Publication types

  • Evaluation Study

MeSH terms

  • Adult
  • Aged
  • Chorionic Gonadotropin / blood*
  • Cohort Studies
  • Cross-Sectional Studies
  • Female
  • Follicle Stimulating Hormone / blood*
  • Humans
  • Internet
  • Male
  • Middle Aged
  • Prostate-Specific Antigen / blood*
  • Proteomics / methods*
  • Software

Substances

  • Chorionic Gonadotropin
  • Follicle Stimulating Hormone
  • Prostate-Specific Antigen